Many diseases require intricate diagnostics and treatment, which can be made much easier with the help of genome editing.
A Human Artificial Chromosome (HAC) is a multi-gene delivery platform for genetically engineering human cells. This platform can accept, deliver and express genes with multiple therapeutic or bio-production functions including, but not limited to: biologics, viral vectors, enzymes, small and large therapeutic RNAs, CRISPR/Cas proteins, and guide RNAs, drug-producing gene clusters, therapeutic proteins, real-time responsive biosensors, and bio-polymer proteins. We have learnt to integrate large DNA sequences into cells reliably, safely, and without mediating an immune response. This technology is nearer than you think: while growing wings is far down the road, edited lab cells can produce effective drugs and improve human lives as early as tonight.
To meet the technical requirements of implementing such a complex gene therapy, at Centaura we are working on developing a novel approach to massive gene editing—the Human Artificial Chromosome.
This ambitious task is both time- and resource-consuming, but once developed, it will allow us to overcome the existing lifespan barrier and achieve a true breakthrough in the extension of human life.
